C-terminal α-MSH tripeptide for inflammation research.
KPV is a tripeptide derived from α-melanocyte-stimulating hormone studied for anti-inflammatory pathways.
Modulates NF-κB signaling and pro-inflammatory cytokine expression in cell models.
Peptide engages target receptor with high affinity.
Downstream intracellular pathways activate.
Gene expression and protein synthesis shift.
Measurable change in the studied biomarker.
Comprehensive review of melanocortin pathway as inflammation control strategy.
Established α-MSH C-terminal fragments as effective non-steroidal anti-inflammatory tools.
Mechanistic and translational review of α-MSH-derived tripeptides.
Documented broad protective effects in immune-mediated inflammatory disease models.
Demonstrated PepT1 transporter-driven uptake of KPV reducing intestinal inflammation.
Reduced colonic inflammation scores at low oral doses via PepT1.
Lyophilized -20°C.
Strictly for in-vitro laboratory and research investigations.
Not approved for diagnostic, therapeutic, or veterinary application.
Handling restricted to licensed researchers and laboratory staff.
Warning — KPV is supplied solely for legitimate laboratory research. Any administration to humans or animals is strictly prohibited and may violate federal, state, or local law. By purchasing, the researcher accepts full responsibility for safe handling, storage, and lawful use.
