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HGH 3ml vial label
Growth HormonePurity ≥98%
Product profile

HGH

Recombinant human growth hormone for somatotropic research.

≥98%
Purity
Lyophilized
Form
-20°C
Storage
Research Use Only. Not for human or veterinary consumption, diagnostic, or therapeutic use.

What it is

Recombinant human growth hormone (rhGH, somatropin) is a 191-amino-acid protein used in research of the somatotropic axis and body-composition modeling.

Pathway Diagram

Mechanism of Action

CRL · MOA-01

Binds the GH receptor, activating JAK2/STAT5 signaling and inducing hepatic IGF-1 production.

  1. Step 01
    Receptor Binding

    Peptide engages target receptor with high affinity.

  2. Step 02
    Signal Cascade

    Downstream intracellular pathways activate.

  3. Step 03
    Cellular Response

    Gene expression and protein synthesis shift.

  4. Step 04
    Observed Outcome

    Measurable change in the studied biomarker.

Primary TargetsGH/IGF-1 axis researchBody-composition studiesLipolysis research

Research highlights

191-amino-acid recombinant somatropin; identical to pituitary hGH.
Reduces visceral and total fat mass in adult research populations.
Increases hepatic IGF-1 via JAK2/STAT5 signaling.
Anabolic and lipolytic effects partially offset by glucose intolerance risk.

Pharmacology snapshot

22,124 Da
Molecular weight
~3.4 hours (SC)
Half-life
SC (research)
Route (research)

Potential research applications

GH/IGF-1 axis research
Body-composition studies
Lipolysis research
Tissue growth modeling

Case studies

Preclinical

GH effects on metabolism review

Cohort: Multi-trial synthesis

Reviewed GH effects on glucose, lipid and protein metabolism.

Outcome

Documented lipolysis, insulin antagonism, and protein-anabolic effects.

Møller & Jørgensen, Endocr Rev 2009;30(2):152–177
ClinicalMulti-month

GH in healthy elderly meta-analysis

Cohort: 31 studies, ~500 adults

Systematic review of GH in healthy older adults.

Outcome

Small reductions in fat mass and increases in lean mass; elevated adverse events.

Liu et al., Ann Intern Med 2007;146(2):104–115
Clinical6 months

GH in men over 60

Cohort: 21 men >60 years

Foundational RCT of GH on body composition in older men.

Outcome

Increased lean mass and decreased adipose with GH vs. control.

Rudman et al., NEJM 1990;323(1):1–6
Handling Protocol

Storage Guidelines

CRL · STR-02

Lyophilized 2–8°C. Reconstituted: 2–8°C, use within 14 days.

Lyophilized
-20°C
Long-term, 24 months
Reconstituted
2–8°C
Refrigerated, 28 days
Light Exposure
Protect
Store in dark vial
Diluent
BAC Water
Sterile, 0.9% benzyl
Best practice — reconstitute with bacteriostatic water, swirl gently, do not shake.
Regulatory Notice

Research Disclaimer

CRL · REG-03
Research Use Only

Strictly for in-vitro laboratory and research investigations.

Not For Human Use

Not approved for diagnostic, therapeutic, or veterinary application.

Qualified Personnel

Handling restricted to licensed researchers and laboratory staff.

Warning — HGH is supplied solely for legitimate laboratory research. Any administration to humans or animals is strictly prohibited and may violate federal, state, or local law. By purchasing, the researcher accepts full responsibility for safe handling, storage, and lawful use.

Document · CRL-REG-03Revision 2026.06 · Clinical Research Labs
Representative Literature

Citations & References

CRL · REF-04
References are representative of peer-reviewed literature and are provided for research context only.
Document · CRL-REF-04Revision 2026.06 · Clinical Research Labs