Selective NNMT inhibitor for metabolic and adipose research.
5-Amino-1-methylquinolinium is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT) investigated for adipose and metabolic research.
Inhibits NNMT, raising intracellular SAM and NAD+ availability and modulating adipocyte energetics.
Peptide engages target receptor with high affinity.
Downstream intracellular pathways activate.
Gene expression and protein synthesis shift.
Measurable change in the studied biomarker.
Characterized selective NNMT inhibition on body weight and adipose biology.
Reduced fat mass and improved insulin sensitivity vs. vehicle.
Tested oral 5-amino-1MQ in established obesity model.
Reversed established obesity by reducing fat-cell size without food-intake changes.
Evaluated NNMT inhibitor effects on satellite-cell compartment in aging muscle.
Increased Pax7+ stem-cell pool and improved regenerative capacity.
Store at -20°C, desiccated and light-protected.
Strictly for in-vitro laboratory and research investigations.
Not approved for diagnostic, therapeutic, or veterinary application.
Handling restricted to licensed researchers and laboratory staff.
Warning — 5-Amino-1MQ is supplied solely for legitimate laboratory research. Any administration to humans or animals is strictly prohibited and may violate federal, state, or local law. By purchasing, the researcher accepts full responsibility for safe handling, storage, and lawful use.
